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Helping leadership realize what they’re missing.
Dr. Manna’s keynotes translate complex biology into clear business implications—giving leaders a new lens on performance, retention, and organizational design.
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The Cost of Ignoring Biology
$26.6 billion is lost each year. That number is incomplete.
The U.S. economy loses billions annually due to menopause-related productivity loss and healthcare costs. That figure does not include the hidden losses organizations absorb every day:
- Senior women reducing hours at peak impact
- Leadership pipeline disruption
- Deferred promotions and stalled advancement
- Early exits from roles that took decades to build
These are not marginal contributors.
They are your most experienced operators.

Across industries, the pattern is clear:
- 31% of first-level supervisors
- 36% of mid-level managers
- 43% of senior executives
have considered leaving their roles due to menopause symptoms.
And they are leaving.
Conviction & Credentials
I am driven by a desire to see more women in leadership. Perimenopause is one of the most significant and least understood obstacles standing in their way. And the workplace is the most effective lever we have to change that.
The financial cost of inaction is real. And, the organizations that move on this know that what’s truly required isn’t just a line item, it’s the willingness to lead through discomfort. That’s a harder lift but the more important one.
— Dr. Manna Semby, ND, IFMCP, MSCP
Founder, Center for Cognitive Resilience | Aruna Personalized Medicine
Former VP, Goldman Sachs | Keynote and TEDx San Diego Speaker | ReCODE 2.0 Certified | Menopause Society Certified Practitioner
Speaking Topics
Perimenopause Is a Brain Event
The science every leader needs to understand about cognitive disruption, decision-making, and performance variability during midlife transition.
The $26 Billion Blind Spot
What menopause is costing your organization—and why most internal estimates are wrong.
Breaking the Silence
Why organizations that address menopause directly outperform those that avoid it.
Men and Menopause
The most important leadership conversation most organizations are not having—and why it matters.
Leadership Longevity
The whole-brain, whole-body case for sustaining executive performance over time.
Formats: Keynotes, executive sessions, ERGs, leadership off-sites
Menopause is driving measurable declines in cognitive performance, retention, and leadership continuity. Most organizations are not equipped to recognize it—let alone respond.
Dr. Manna Semby brings clinical precision and executive experience to one of the most overlooked drivers of organizational performance.

Book Dr. Manna Semby
Dr. Manna speaks at corporate events, leadership conferences, ERG gatherings, professional association meetings, and executive off-sites. Engagements are available in-person and virtually.
Book
Coming Soon
Fixing the Perimenopause Broken Rung
What Unaddressed Perimenopause Costs Women and Organizations
The book that gives organizations and the women who lead them the science, the framework, and the tools to close the leadership gap that nobody is talking about.

Make a Difference in Your Organization
Industry data puts the annual organizational cost of menopause at $26 billion in the US. That number is conservative. Your share of it is real and calculable.
But the organizations that truly move on this know that the math is where the conversation starts, not where it ends.
The question is whether your organization is ready to lead all the way through it.

Book Dr. Manna Semby
Dr. Manna speaks at corporate events, leadership conferences, ERG gatherings, professional association meetings, and executive off-sites. Engagements are available in-person and virtually.
















